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Table 4 Adverse events

From: Apatinib treatment efficiently delays biochemical-only recurrent ovarian cancer progression

Adverse events

Grades

1

(n, %)

2

(n, %)

3

(n, %)

4

(n, %)

Total

(n, %)

Hand-foot syndrome

5 (12.2%)

9 (22.0%)

5 (12.2%)

0 (0%)

19 (46.4%)

Mucositis

3 (7.3%)

6 (14.6%)

8 (19.5%)

0 (0%)

17 (41.5%)

Anorexia

12 (29.3%)

3 (7.3%)

1 (2.4%)

0 (0%)

16 (39.0%)

Fatigue

4 (9.8%)

7 (17.1%)

5 (12.2%)

0 (0%)

16 (39.0%)

Proteinuria

11 (26.8%)

4 (9.8%)

0 (0%)

0 (0%)

15 (36.6%)

Hypertension

5 (12.2%)

6 (14.6%)

3 (7.3%)

0 (0%)

14 (34.1%)

Pain

6 (14.6%)

4 (9.8%)

1 (2.4%)

0 (0%)

11 (26.8%)

Thrombocytopenia

6 (14.6%)

3 (7.3%)

2 (4.9%)

0 (0%)

11 (26.8%)

Neutropenia

2 (4.9%)

2 (4.9%)

1 (2.4%)

0 (0%)

5 (12.2%)

Transaminase increased

1 (2.4%)

3 (7.3%)

1 (2.4%)

0 (0%)

5 (12.2%)

Diarrhea

1 (2.4%)

2 (4.9%)

0 (0%)

0 (0%)

3 (7.3%)