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Table 3 Association between tomographic response and the difference (delta) between HE4alevels (n=53)

From: Kinetics of HE4 and CA125 as prognosis biomarkers during neoadjuvant chemotherapy in advanced epithelial ovarian cancer

  Univariate Multivariateb
HE4 Est CI 95% p Est CI 95% p
Between basal and first cycle 0.182 0.033, 0.330 0.017 0.194 0.019, 0.368 0.030
Between basal and second cycle 0.116 -0.013, 0.245 0.080 0.128 -0.013, 0.269 0.077
Between basal and third cycle 0.090 0.060, 0.240 0.244 0.108 -0.058, 0.274 0.203
Between first and second cycle 0.069 -0.125, 0.263 0.485 0.203 -0.092, 0.498 0.179
  1. CI confidence interval
  2. a Transformed by decimal logarithm
  3. b Adjusted for age at diagnosis, basal ECOG, smoking, histological subtype and FIGO stage
  4. Those p values with statistical significance (less than 0.05) are marked in bold