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Table 3 Association between tomographic response and the difference (delta) between HE4alevels (n=53)

From: Kinetics of HE4 and CA125 as prognosis biomarkers during neoadjuvant chemotherapy in advanced epithelial ovarian cancer

 

Univariate

Multivariateb

HE4

Est

CI 95%

p

Est

CI 95%

p

Between basal and first cycle

0.182

0.033, 0.330

0.017

0.194

0.019, 0.368

0.030

Between basal and second cycle

0.116

-0.013, 0.245

0.080

0.128

-0.013, 0.269

0.077

Between basal and third cycle

0.090

0.060, 0.240

0.244

0.108

-0.058, 0.274

0.203

Between first and second cycle

0.069

-0.125, 0.263

0.485

0.203

-0.092, 0.498

0.179

  1. CI confidence interval
  2. a Transformed by decimal logarithm
  3. b Adjusted for age at diagnosis, basal ECOG, smoking, histological subtype and FIGO stage
  4. Those p values with statistical significance (less than 0.05) are marked in bold