Decreased SFRP5 correlated with excessive metabolic inflammation in polycystic ovary syndrome could be reversed by metformin: implication of its role in dysregulated metabolism

Table 2 Partial correlations analysis of variables associated with circulating SFRP5 levels in study population

Item	Plasma SFRP5		Plasma SFRP5 (age-adjusted)		Plasma SFRP5 (age-BMI-adjusted)		Plasma SFRP5 (age-BMI-WHR-adjusted)
Item	r	P-value	r	P-value	r	P-value	r	P-value
Age(years)	0.174	0.083
BMI (Kg/m²)	-0.492	< 0.001	-0.524	< 0.001
WHR	-0.271	0.006	-0.296	0.003	0.036	0.725
AMH (ng/ml)	0.501	< 0.001	-0.498	< 0.001	-0.284	0.005	-0.285	0.005
FAI	-0.566	< 0.001	-0.560	< 0.001	-0.390	< 0.001	-0.400	< 0.001
FINS (Uiu/ml)	-0.452	< 0.001	-0.464	< 0.001	-0.158	0.121	-0.161	0.114
2-h INS (Uiu/ml)	-0.450	< 0.001	-0.459	< 0.001	-0.154	0.131	-0.161	0.115
FBG (mmol/l)	-0.510	< 0.001	-0.568	< 0.001	-0.400	< 0.001	-0.401	< 0.001
2-hBG (mmol/l)	-0.444	< 0.001	-0.484	< 0.001	-0.271	0.007	-0.274	0.007
HOMA-IR	-0.484	< 0.001	-0.505	< 0.001	-0.218	0.031	-0.223	0.028
IL6(pg/ml)	-0.550	< 0.001	-0.572	< 0.001	-0.463	< 0.001	-0.465	< 0.001
TNFα (ng/ml)	-0.708	< 0.001	-0.707	< 0.001	-0.601	< 0.001	-0.600	< 0.001

ISSN: 1757-2215