Skip to main content

Table 1 Patients characteristics and their embryological and PGT analyses

From: Can expelled cells/debris from a developing embryo be used for PGT?

Patient

Age

Disease/Etiology

Embryo #

Day 3 quality

Day 3 Diagnosis

 

Day 5/6 quality

Day 5/6 Diagnosis

(A)

 A

33

2p 16.3 microdeletion

1

7A

Affected

Embryo

3BB

Affected

Debris

2 cells

Affected

2

8A

Affected

Embryo

6AA

Affected

Debris

4 cells

Affected

 B

40

Marfan Syndrome

3

8A

Affected & Aneuploidy

Embryo

4AB

Affected & Aneuploidy

Debris

3 cells

Affected

 C

43

Ataxia Telengiectasia

4

9A

Unaffected & Aneuploidy

Embryo

4BA

Unaffected & Aneuploidy

Debris

3 cells

Unaffected & Aneuploidy

 D

29

Creutzfeld Jakob Disease

5

8A

Affected

Embryo

6AA

Affected

Debris

5 cells

Affected

 E

34

Machado Joseph Disease

6

7A

Affected

Embryo

G2

Affected

Debris

Cell fragments

Affected & Aneuploidy

 F

37

Neurofibromatosis type I

7

8A

Affected

Embryo

6BB

Affected

Debris

4 cells

Affected & Aneuploidy

8

8A

Affected

Embryo

6AB

Affected

Debris

3 cells

Affected & Aneuploidy

(B)

 B

40

Marfan Syndrome

9

 

Affected & Aneuploidy

Embryo

6BB

Affected

Debris

8 cells

Allele drop out

 G

32

Synopolydactyly II

10

 

Affected

Embryo

6AA

Affected

Debris

Cell fragments

Allele drop out

 H

33

Huntington’s disease

11

 

Affected

Embryo

6AA

Affected

Debris

2 cells

Foreign DNA & Aneuploidy

 I

24

Nager Syndrome

12

 

Affected

Embryo

4BC

Affected

Debris

2 cells

Undetectable

13

 

Affected

Embryo

6BA

Affected

Debris

2 cells

Allele drop out

14

 

Affected

Embryo

5BB

Affected

Debris

3 cells

Unsatisfactory diagnosis