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Fig. 2 | Journal of Ovarian Research

Fig. 2

From: Hsa_circ_0004712 downregulation attenuates ovarian cancer malignant development by targeting the miR-331-3p/FZD4 pathway

Fig. 2

Hsa_circ_0004712 knockdown blocked OC development in vitro. A In si- hsa_circ_0004712 transfected cells, the expression of hsa_circ_0004712 was measured by qRT-PCR. B and C Cell proliferation ability was assessed by CCK-8 assay and colony formation assay. D Cell apoptosis was checked by flow cytometry assay. E Cell invasion was assessed by transwell assay. F Cell migration was assessed by wound healing experiment. G The expression of C-caspase, MMP2 and MMP9 was detected by western blot. H The activities of MMP2 and MMP9 were determined by gelatin zymography analysis. *P < 0.05

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