|
Number of patients, n (%)
|
633(75.8)
|
116(13.9)
|
86(10.3)
| | | | |
|
Maternal age, y
|
33.22 ± 4.88
|
32.97 ± 4.58
|
31.14 ± 4.07
|
0.001
|
1.00
|
< 0.001*
|
0.016*
|
|
Body mass index, kg/m2
|
22.31 ± 3.24
|
22.48 ± 2.94
|
22.49 ± 3.20
|
0.508
| | | |
|
Baseline FSH, mIU/mL
|
9.32 ± 3.74
|
8.18 ± 2.25
|
8.67 ± 2.90
|
0.016
|
0.024*
|
0.447
|
1.00
|
|
Antral follicle count (AFC)
|
7.07 ± 2.37
|
9.01 ± 2.64
|
10.01 ± 3.70
|
< 0.001
|
< 0.001*
|
< 0.001*
|
1.00
|
|
AMH level, ng/ml
|
0.84 ± 0.24
|
0.93 ± 0.20
|
0.92 ± 0.25
|
< 0.001
|
< 0.001*
|
0.001*
|
1.00
|
|
Duration of infertility, years
|
3.36 ± 3.01
|
3.58 ± 2.81
|
3.47 ± 2.46
|
0.208
| | | |
|
Infertility diagnosis
| | | |
0.351
| | | |
|
Primary infertility, %
|
61.0(386/633)
|
54.3(63/116)
|
57.0(49/86)
| | | | |
|
Secondary infertility, %
|
39.0(247/633)
|
45.7(53/116)
|
43.0(37/86)
| | | | |
|
Gn duration, days
|
9.48 ± 1.53
|
10.09 ± 1.87
|
11.03 ± 1.70
|
< 0.001
|
0.004
|
< 0.001*
|
< 0.001*
|
|
Gonadotropin dose, IU
|
2883 ± 768
|
2878 ± 786
|
3257 ± 790
|
< 0.001
|
1.00
|
0.001*
|
< 0.001*
|
|
E2 on hCG, pg/mL
|
1558 ± 885
|
1949 ± 1049
|
1618 ± 996
|
0.001
|
< 0.001*
|
1.00
|
0.039*
|
|
P on hCG day, ng/mL
|
0.73 ± 0.39
|
0.78 ± 0.38
|
0.73 ± 0.37
|
0.223
|
< 0.001*
|
1.00
|
0.039*
|
|
No. of oocytes retrieved
|
5.87 ± 3.36
|
6.95 ± 3.66
|
7.91 ± 4.80
|
< 0.001
|
0.007*
|
< 0.001*
|
0.960
|
|
No. of MII oocytes
|
5.20 ± 3.03
|
5.93 ± 3.21
|
6.94 ± 4.40
|
< 0.001
|
0.056
|
0.001*
|
0.690
|
|
Oocyte maturation rate
|
0.90 ± 0.16
|
0.87 ± 0.19
|
0.88 ± 0.15
|
0.054
| | | |
|
The number of 2PN
|
3.58 ± 2.54
|
3.92 ± 2.62
|
4.78 ± 3.57
|
0.015
|
0.434
|
0.022*
|
0.781
|
|
Normal fertilization rate
|
0.64 ± 0.28
|
0.59 ± 0.27
|
0.64 ± 0.24
|
0.208
| | | |
|
Good-quality embryo rate on day 3
|
0.50 ± 0.34
|
0.44 ± 0.31
|
0.48 ± 0.27
|
0.557
| | | |
|
blastocyst formation rate
|
0.56 ± 0.38
|
0.54 ± 0.36
|
0.54 ± 0.35
|
0.737
| | | |
|
No. of available embryos
|
3.58 ± 2.49
|
3.94 ± 2.61
|
4.76 ± 3.58
|
0.017
|
0.412
|
0.027*
|
0.872
|
|
Available embryo rate
|
0.64 ± 0.28
|
0.60 ± 0.26
|
0.63 ± 0.24
|
0.207
| | | |
|
No. of embryos transferred
|
1.00 ± 0.76
|
1.24 ± 0.81
|
1.19 ± 0.68
|
0.002
|
0.005*
|
0.126
|
1.00
|
|
Endometrial thickness, mm
|
10.92 ± 2.57
|
11.40 ± 2.51
|
11.28 ± 2.38
|
0.022
|
0.068
|
0.182
|
1.00
|
|
Cumulative live birth rate, %
|
35.5(225/633)
|
37.9(44/116)
|
51.2(44/86)
|
0.019
|
1.00
|
0.015*
|
0.165
|
|
Live birth rate, %b
|
26.2(166/633)
|
31.3(36/115)
|
45.3(39/86)
|
0.001
|
0.808
|
0.001*
|
0.090
|
|
Live birth rate, %c
|
36.6(166/454)
|
40.9(36/88)
|
53.4(39/73)
|
0.022
|
1.00
|
0.019*
|
0.317
|
|
Clinical pregnancy rate, %b
|
32.2(204/633)
|
37.9(44/116)
|
51.2(44/86)
|
0.002
|
0.710
|
0.002*
|
0.154
|
|
Clinical pregnancy rate, %c
|
44.9(204/454)
|
49.4(44/89)
|
60.3(44/73)
|
0.047
|
1.00
|
0.045*
|
0.509
|
