Table 3 Basic and cycle characteristics and pregnancy outcomes in the different controlled ovarian stimulation protocols in Group 3

Number of patients, n (%)

414(92.8)

12(2.7)

20(4.5)

Maternal age, y

33.21 ± 4.80

34.08 ± 4.30

31.80 ± 4.94

Body mass index, kg/m²

21.74 ± 2.87

21.73 ± 2.61

21.85 ± 2.38

Baseline FSH, mIU/mL

8.62 ± 2.80

7.18 ± 1.55

7.53 ± 2.15

Antral follicle count (AFC)

3.32 ± 0.91

3.17 ± 1.40

3.25 ± 1.33

AMH level, ng/ml

2.38 ± 1.32

4.01 ± 2.45

3.28 ± 1.75

Duration of infertility, years, median (IQR)

3.00(2.00–5.00)

3.00(1.00–4.00)

2.00(1.00–4.00)

Infertility diagnosis

Primary infertility, %

56.8(235/414)

66.7(8/12)

75.0(15/20)

Secondary infertility, %

43.2(179/414)

33.3(4/12)

25.0(5/20)

Gn duration, days

9.45 ± 1.60

10.00 ± 1.48

11.35 ± 1.60

Gonadotropin dose, IU

2777 ± 698

2741 ± 731

3291 ± 860

E2 on hCG day, pg/mL

1917 ± 971

3817 ± 2712

2180 ± 1243

P on hCG day, ng/mL

0.82 ± 0.44

1.00 ± 0.39

0.99 ± 0.43

No. of oocytes retrieved

6.77 ± 3.54

9.58 ± 5.33

8.85 ± 4.21

No. of MII oocytes

6.03 ± 3.30

9.33 ± 5.50

7.55 ± 3.44

Oocyte maturation rate

0.89 ± 0.15

0.96 ± 0.08

0.88 ± 0.14

The number of 2PN

4.19 ± 2.76

6.42 ± 4.06

4.65 ± 2.98

Normal fertilization rate

0.65 ± 0.26

0.70 ± 0.19

0.56 ± 0.22

blastocyst formation rate

0.61 ± 0.35

0.52 ± 0.37

0.66 ± 0.24

No. of available embryos

4.17 ± 2.72

6.58 ± 3.58

4.70 ± 2.60

Available embryo rate

0.66 ± 0.29

0.73 ± 0.15

0.57 ± 0.21

No. of embryos transferred

0.93 ± 0.75

1.00 ± 0.85

1.10 ± 0.91

Endometrial thickness, mm

10.81 ± 2.49

11.23 ± 2.21

12.18 ± 2.52

Cumulative live birth rate, %

35.5(147/414)

58.3(7/12)

40.0(8/20)

Live birth rate, %^b

23.0(95/413)

41.7(5/12)

25.0(5/20)

Live birth rate, %^c

33.6(95/283)

62.5(5/8)

38.5(5/13)

Clinical pregnancy rate, %^b

27.8(115/414)

41.7(5/12)

30.0(6/20)

Clinical pregnancy rate, %^c

40.5(115/284)

62.5(5/8)

46.2(6/13)