Fig. 3
From: CXCL2-mediated ATR/CHK1 signaling pathway and platinum resistance in epithelial ovarian cancer
CXCL2 overexpression inhibites cell apoptosis induced by cisplatin. A and B The cell apoptosis rate increased in cisplatin-senstive cells with CXCL2 overexpressing or incubating with recombinant CXCL2 (CXCL2, 50 ng/ml) for 48 h. C and D The cell apoptosis rate decreased in cisplatin-resistant cells with CXCL2 knocking down or incubating with CXCL2 neutralizing antibody (5 µg/mL) for 48 h