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Fig. 2 | Journal of Ovarian Research

Fig. 2

From: Effects of single and multiple transplantations of human umbilical cord mesenchymal stem cells on the recovery of ovarian function in the treatment of premature ovarian failure in mice

Fig. 2

Changes of ovary weight in the once intravenous group and the multiple intravenous groups over 60 days. a, b, c, d In the once intravenous group, ovarian volume of mice was remarkably increased at 7, 14, 21, 28 days post-induction, respectively. n = 5. f, g The multiple intravenous groups showed significantly increased of ovarian volume at 28, 60 days post-induction, respectively. n = 5. e, h The histogram represents the results of statistical analysis of ovarian weight by single and multiple injections, respectively. Organ coefficient = organ weight/weight, n = 5. i Pregnancy rate of POF mice treated with D28 and D60, 1xMSC and 3xMSC. n = 5. j Number of litters per litter of POF treated with 1xMSC. n = 5. k Number of litters per litter of POF treated with 3xMSC. n = 5. *P < 0.05; **P < 0.01. 1xMSC: Single transplantation of hUC-MSC; 3xMSC: Multiple transplantation of hUC-MSC

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