Fig. 5

The effects of hUC-MSC transplantation on ovarian morphology and follicular development in the POF mouse. a Representative H&E micrographs of ovary sections from the once intravenous group over 60 days showing all stages of follicles in Sham group, stroma, and atretic primordial or primary follicles in POF group, primordial as well as primary and large antral follicles in MSCs group. n = 5. Original magnification: 100 × . b Follicle counts at all stages on the 14th day. n = 5. c Follicle counts at all stages on the 21th day. n = 5. d Follicle counts at all stages on the 28th day. n = 5. e Follicle counts at all stages on the 60th day. n = 5. f Ovarian sections of the multiple intravenous injection group. Original magnification: 100 × . n = 5. g Morphological follicle count of mouse ovaries, the follicle counts at all stages on the 28th day. n = 5. h Morphological follicle count of mouse ovaries, the follicle counts at all stages on the 60th day. n = 5. *P < 0.05; **P < 0.01; ***P < 0.001. 1xMSC: Single transplantation of hUC-MSC; 3xMSC: Multiple transplantation of hUC-MSC