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Fig. 3 | Journal of Ovarian Research

Fig. 3

From: CircSETDB1 knockdown inhibits the malignant progression of serous ovarian cancer through miR-129-3p-dependent regulation of MAP3K3

Fig. 3

CircSETDB1 was associated with miR-129-3p in A2780 and SKOV3 cells. A Schematic illustration showed the putative binding sites of circSETDB1 in miR-129-3p and mutated sites of circSETDB1 sequence. B and C Dual-luciferase reporter and RIP assays were conducted to confirm the interaction between circSETDB1 and miR-129-3p in A2780 and SKOV3 cells. D and E MiR-129-3p expression was detected by qRT-PCR in SOC tissues (N = 73), normal fallopian tube tissues (N = 73) and IOSE-80, A2780 and SKOV3 cells. F The correlation between circSETDB1 and miR-129-3p expression was determined by Spearman correlation analysis in SOC tissues. *P < 0.05

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