Fig. 4

CircSETDB1 knockdown repressed SOC cell processes by interacting with miR-129-3p. A The interfering efficiency of miR-129-3p inhibitor was determined by qRT-PCR in A2780 and SKOV3 cells. B-H Both A2780 and SKOV3 cells were transfected with si-NC, si-circSETDB1#1, si-circSETDB1#1 + inhibitor NC or si-circSETDB1#1 + miR-129-3p inhibitor. B MiR-129-3p expression was detected by qRT-PCR. C and D Cell proliferation was determined by CCK-8 and EDU assays. E Flow cytometry analysis was performed to detect cell apoptotic rate. F and G The invasion and migration of A2780 and SKOV3 cells were investigated by transwell invasion and wound-healing assays, respectively. H The protein abundance of MMP9 and MMP2 was detected by western blot analysis. *P < 0.05