Journal of Ovarian Research

Table 2 Frequency of TP53, PIK3CA, KRAS, PTEN and CTNNB mutations according to demographic and clinicopathological characteristics

From: Identification and clinical significance of somatic oncogenic mutations in epithelial ovarian cancer

	Age		P value	Stage		P value	Histology				P value
	< 60	≥ 60	P value	I/II	III/IV	P value	Serous	Clear cell	Endometrioid	Mucinous	P value
TP53
WT	25	20		24	21		7	19	16	3
MT	14	21	0.17	10	25	0.026	25	2	4	4	< 0.001
PIK3CA
WT	26	32		19	39		32	9	10	7
MT	13	9	0.25	15	7	0.004	0	12	10	0	< 0.001
KRAS
WT	30	31		21	40		31	16	14	0
MT	9	10	0.89	13	6	0.009	1	5	6	7	< 0.001
PTEN
WT	31	41		31	41		32	19	15	6
MT	8	0	0.002	4	4	0.71	0	2	5	1	0.033
CTNNB1
WT	32	40		27	45		32	19	14	7
MT	7	1	0.021	8	0	0.001	0	2	6	0	0.004

WT Wild-type, MT Mutant

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ISSN: 1757-2215

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