Fig. 1

Implications of Polycystic ovary syndrome in women’s life. The pulsatile release of gonadotropin-releasing hormone (GnRH) from the hypothalamus often leads to hyperandrogenism and polycystic ovaries through hypersecretion of luteinizing hormone indicating hypothalamic defects. Low levels of sex hormone-binding globulin (SHBG) and adrenal androgens might also result in hyperandrogenism which is mostly observed in PCOS. Abbreviations: LH, luteinizing hormone; GnRH, gonadotropin-releasing hormone; PCOS, polycystic ovary syndrome, SHBG; sex hormone-binding globulin