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Table 1 Main clinical characteristics of the study groups

From: Lipidomics analysis of human follicular fluid form normal-weight patients with polycystic ovary syndrome: a pilot study

 

Controls(n = ten)

PCOS(n = eight)

P-value

Age (years)

28.80 ± 2.74

27.12 ± 3.40

0.26

BMI (kg/m2)

20.96 ± 1.99

19.96 ± 1.77

0.28

LH (mIU/mL)

4.20 ± 2.61

5.57 ± 2.48

0.22

FSH (mIU/mL)

5.86 ± 1.64

6.66 ± 2.21

0.39

LH/FSH

0.76 ± 0.63

0.93 ± 0.49

0.28

E2(pg/mL)

44.3 ± 40.69

68.75 ± 39.91

0.22

T (ng/mL)

0.49 ± 0.14

0.53 ± 0.11

0.52

Glucose (mmol/l)

4.83 ± 0.42

5.19 ± 0.46

0.52

Cholesterol (mmol/L)

4.25 ± 0.25

4.12 ± 0.32

0.77

triglyceride (mmol/L)

0.87 ± 0.28

0.88 ± 0.40

0.96

HDL-C (mmol/L)

1.47 ± 0.28

1.56 ± 0.54

0.64

LDL-C (mmol/L)

2.40 ± 0.71

2.02 ± 0.41

0.17

AMH (ng/mL)

3.52 ± 1.12

12.97 ± 3.42

< 0.001*

No.of Oocyte retrieve

13.2 ± 5.59

22.3 ± 5.99

0.004*

Normal fertilization Rate(%)

87.03 ± 0.18

79.24 ± 0.16

0.40

Cleavage Rate(%)

95.08 ± 0.57

87.76 ± 0.11

0.07

Embryo top-quality Rate(%)

43.44 ± 0.21

53.42 ± 0.27

0.43

  1. *is indicated p < 0.05 values. Data presented as mean ± standard deviation (SD)
  2. Abbreviations: BMI body mass index; FSH follicle-stimulating hormone; LH luteinizing hormone; E2 estradiol; T testosterone; HDL-C high-density lipoprotein cholesterol; LDL-C low-density lipoprotein cholesterol; AMH anti-Mullerian hormone
  3. normal fertilization rate = no. oocytes with 2PN and 2 PB/no. COC inseminated× 100%; cleavage rate = no. cleaved embryos on Day 2/no. 2PN/2 PB oocytes on Day 1 × 100%; embryo top-quality rate = top quality embryos/no. normally fertilized oocytes× 100%.