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Fig. 7 | Journal of Ovarian Research

Fig. 7

From: Circ_0061140 knockdown inhibits tumorigenesis and improves PTX sensitivity by regulating miR-136/CBX2 axis in ovarian cancer

Fig. 7

Circ_0061140 silencing enhanced the inhibitory effects of PTX on tumor growth in vivo. (A and B) The effects of circ_0061140 absence on the volume and weight of tumors after PTX treatment were revealed. (C and D) QRT-PCR was employed to determine the impacts of circ_0061140 silencing on the expressions of circ_0061140 and miR-136 under PTX exposure in vivo. (E and F) The mRNA and protein expressions of CBX2 were uncovered by qRT-PCR and western blot, respectively, in forming tumors from sh-NC, sh-NC + PTX, sh-circ_0061140 or sh-circ_0061140 + PTX group. *P < 0.05

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