Fig. 4

Circ-FURIN mediated BCL2 through sponging miR-195-5p. A The targeted relationship between circ-FURIN and miR-195-5p was predicted using bioinformatics and confirmed by dual-luciferase reporter assay. B RNA pull-down assay was utilized to confirm the binding of circ-FURIN to miR-195-5p. C The targeted relationship between miR-195-5p and BCL2 was predicted using bioinformatics and verified using dual-luciferase reporter assay. D RNA pull-down assay was utilized to confirm the binding of circ-FURIN to miR-195-5p. E MiR-195-5p was detected in GCs from patients with PCOS and healthy control using RT-qPCR. F MiR-195-5p was examined in IOSE80 and KGN cell lines using RT-qPCR. G The transfection efficiency was tested using RT-qPCR in cells transfection of si-circ-FURIN and si-circ-FURIN + miR-195-5p inhibitor. **P < 0.01