Fig. 3

Impact of ICS and cisplatin on ascites accumulation. Ascites volume was measured at the time of necropsy on day 42 or at required euthanasia because of complications of disease progression. Volumes were categorized as minimal (≤1.0 ml), moderate (> 1.0 ml and <10 ml), or massive (≥10 ml). Pie charts show the relative proportion of mice with each category of ascites volume in the ICS (surgery) arm and anesthesia control (A) arm (χ²_{(2, n=56)}=6.552, p = 0.0378). The stacked bar graphs present the relative distribution of ascites categories within each individual treatment group. The numbers in parentheses at the top of each bar indicate the number of animals measured per group. C₀ = cisplatin on day 0, C₇ = cisplatin on day 7, C₂₈ = cisplatin on day 28