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Fig. 5 | Journal of Ovarian Research

Fig. 5

From: Chronic exposure to perfluorohexane sulfonate leads to a reproduction deficit by suppressing hypothalamic kisspeptin expression in mice

Fig. 5

Effect of PFHxS exposure on the LH surge and the expression of kisspeptin. A Average serum LH level standardized by 1600 h. *P < 0.05 vs. The control mice (n = 6/group, two-way ANOVA). B Representative image of kisspeptin immunostaining in AVPV. Arrows indicate AVPV-kisspeptin+ cells. Scale bar = 100 μm. C Relative levels of AVPV-kiss1/GAPDH mRNA. D Representative image of kisspeptin immunostaining in the ARC. Arrows indicate ARC-kisspeptin+ cells. Scale bar = 100 μm. E Relative levels of ARC-kiss1/GAPDH mRNA. *P < 0.05 vs. the control mice (n = 6/group, Student’s t-test)

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