Fig. 6

miR-149-3p promoted OC cells tumorigenesis and growth in vivo. A-C. A2780/DDP cells were grown in the inguinal subcutaneous region of nude mice to establish tumor growth model. Tumor volume growth curves (A), representative images (B) and tumor weight (C). D The mRNA expression of miR-149-3p, TIMP2 and CDKN1A was detected by q-PCR. E. Western blot was performed to detect the protein expression of TIMP2 and CDKN1A. *P < 0.05. All experiments were repeated three times with similar results