Table 1 Expression of SALL4 and ALDH1A1 (Intensity of staining, percentage of positive tumor cells, and H-score) in serous ovarian carcinoma (SOC), benign ovarian tumors, and normal tissue samples
Scoring system | Serous ovarian carcinoma N (%) SALL4 | Benign ovarian tumors N (%) SALL4 | Normal Samples N (%) SALL4 | P-value | Serous ovarian carcinoma N (%) ALDH1A1 | Benign ovarian tumors N (%) ALDH1A1 | Normal Samples N (%) ALDH1A1 | P-value |
|---|---|---|---|---|---|---|---|---|
Intensity of staining | ||||||||
 Negative (0) | 12 (26.7) | 35 (94.6) | 20 (100.0) | < 0.001 | 14 (31.1) | 4 (26.7) | 0 (0.0) | 0.048 |
 Weak (+ 1) | 20 (44.4) | 1 (2.7) | 0 (0.0) | 8 (17.8) | 1 (6.7) | 3 (15.0) | ||
 Moderate (+ 2) | 9 (20.0) | 1 (2.7) | 0 (0.0) | 4 (8.9) | 2 (13.3) | 7 (35.0) | ||
 Strong (+ 3) | 4 (8.9) | 0 (0.0) | 0 (0.0) | 19 (42.2) | 8 (53.3) | 10 (50.0) | ||
Percentage of positive tumor cells | ||||||||
 < 25% | 24 (53.3) | 35 (94.6) | 0 (0.0) | < 0.001 | 21 (46.7) | 5 (33.3) | 0 (0.0) | 0.254 |
 25–50% | 10 (22.2) | 1 (2.7) | 0 (0.0) | 4 (8.9) | 0 (0.0) | 2 (10.0) | ||
 51- 75% | 3 (6.7) | 1 (2.7) | 0 (0.0) | 1 (2.2) | 0 (0.0) | 1 (5.0) | ||
 >  75% | 8 (17.8) | 0 (0.0) | 20 (100.0) | 19 (42.2) | 10 (66.7) | 17 (85.0) | ||
H-score cut off =100 | ||||||||
 Low | 33 (73.3) | 35 (94.6) | 0 (0.0) | < 0.001 | 25 (55.6) | 5 (33.3) | 10 (50.0) | 0.050 |
 High | 12 (26.7) | 2 (5.4) | 0 (0.0) | 20 (44.4) | 10 (66.7) | 10 (50.0) | ||
Total | 45 | 37 | 20 | 45 | 15 | 20 | ||