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Fig. 4 | Journal of Ovarian Research

Fig. 4

From: Down-regulation of ZNF252P-AS1 alleviates ovarian cancer progression by binding miR-324-3p to downregulate LY6K

Fig. 4

ZNF252P-AS1 binds to and negatively regulates miR-324-3p. A. DbDEMC online tool was used to analyze the differential expression profile of miR-324-3p in various cancers compared to standard controls. B. Kaplan–Meier survival curve for TCGA-OV dataset miR-324-3p level in ovarian cancer tissues. C. qRT-PCR investigated the relative level of miR-324-3p in IOSE80 cells, SKOV3 cells, A2780 cells and OVCAR3 cells. D. Binding sites between ZNF252P-AS1 and miR-324-3p were estimated using the miRDB database. E. A luciferase assay established the binding relationship between ZNF252P-AS1 and miR-324-3p. F. miR-324-3p level was measured by qRT-PCR in SKOV3 cells and A2780 cells. Data were presented as mean ± SD. **p < 0.01

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