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Table 3 Effect of co-administration of nicotine and ginseng on apoptotic genes in mouse ovary

From: Ginseng alleviates folliculogenesis disorders via induction of cell proliferation and downregulation of apoptotic markers in nicotine-treated mice

Groups

Bax

Bcl-2

Cyt c

Bax/Bcl-2

Control

2.62 ± 0.2b

4.82 ± 2.60

2.47 ± 0.78b

0.53 ± 0.23b

Sham

0.83 ± 0.33b

3.72 ± 1.93

2.27 ± 1.46b

0.26 ± 0.14b

Nicotine

5.88 ± 1.16a

2.44 ± 1.02

19.07 ± 5.54a

1.60 ± 0.19a

Nicotine + Ga

1.39 ± 0.52b

10.22 ± 1.26

4.75 ± 2.87b

0.13 ± 0.04b

Nicotine + Gb

1.25 ± 0.89b

16.85 ± 4.83ab

3.34 ± 1.75b

0.08 ± 0.05b

  1. Data are expressed as Mean ± S.E.; Ga: ginseng 0.5 gr/kg, Gb: ginseng 1 gr/kg. asignificant in compare to controls: P = 0.01; bsignificant in compare to nicotine P = 0.03