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Fig. 10 | Journal of Ovarian Research

Fig. 10

From: Up-regulation of MTHFD2 is associated with clinicopathological characteristics and poor survival in ovarian cancer, possibly by regulating MOB1A signaling

Fig. 10

MTHFD2 accelerated the cell growth, invasion, and migration in ovarian cancer through MOB1A. A The expression of MTHFD2 was significantly reduced in ovarian cancer cells transfected with si-MTHFD2. B The cell proliferation of ovarian cancer cell lines transfected with different interference sequences, cell proliferation was the weakest in si-MTHFD2 group. C and D Invasion and migration assays of ovarian cancer cells under different interference conditions. E and F The western blot revealed MOB1A expression was significantly decreased in si-MTHFD2 group ovarian cells. *P < 0.05 and **P < 0.01, compared with NC group

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Journal of Ovarian Research

ISSN: 1757-2215

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