From: A prognostic model of patients with ovarian mucinous adenocarcinoma: a population-based analysis
Variables | Number of patients | Univariate analysis | Multivariate analysis | ||
---|---|---|---|---|---|
HR (95% CI) | P value | HR (95% CI) | P value | ||
Age | |||||
12–57 | 578 | Reference | Reference | ||
58–70 | 213 | 1.374 (0.989–1.908) | 0.058 | 1.390 (0.978–1.975) | 0.067 |
71–92 | 126 | 2.848 (2.050–3.956) | < 0.001 | 2.557 (1.720–3.800) | < 0.001 |
Race | |||||
Black | 70 | Reference | Reference | ||
White | 742 | 0.552 (0.365–0.834) | 0.005 | 0.545 (0.351–0.846) | 0.007 |
Other | 105 | 0.368 (0.202–0.672) | 0.001 | 0.575 (0.308–1.074) | 0.083 |
Marital | |||||
Divorced | 94 | Reference | Reference | ||
Married | 461 | 0.712 (0.470–1.080) | 0.110 | 0.740 (0.474–1.156) | 0.186 |
Separated | 5 | 1.143 (0.272–4.800) | 0.855 | 0.707 (0.150–3.333) | 0.661 |
Single | 265 | 0.555 (0.350–0.882) | 0.013 | 0.706 (0.431–1.157) | 0.167 |
Unmarried or Domestic Partner | 1 | 1.596*10^(−6)(0-Inf) | 0.993 | 7.135*10^(−7)(0-Inf) | 0.998 |
Widowed | 91 | 1.081 (0.643–1.817) | 0.769 | 0.502 (0.279–0.905) | 0.022 |
Laterality | |||||
unilateral | 807 | Reference | Reference | ||
bilateral | 110 | 6.017 (4.526–7.998) | < 0.001 | 1.215 (0.863–1.710) | 0.265 |
Grade | |||||
I | 349 | Reference | Reference | ||
II | 405 | 1.504 (1.069–2.117) | 0.019 | 1.279 (0.898–1.820) | 0.172 |
III | 132 | 3.809 (2.639–5.499) | < 0.001 | 2.092 (1.390–3.149) | < 0.001 |
IV | 31 | 3.312 (1.805–6.078) | < 0.001 | 2.720 (1.414–5.233) | 0.003 |
T stage | |||||
T1 | 684 | Reference | Reference | ||
T2 | 66 | 4.531 (2.878–7.134) | < 0.001 | 2.858 (1.729–4.724) | < 0.001 |
T3 | 166 | 14.750 (10.886–19.986) | < 0.001 | 7.779 (5.104–11.855) | < 0.001 |
TX | 1 | 2.358*10^(−6)(0-Inf) | 0.995 | 1.483*10^(−7)(0-Inf) | 0.997 |
N stage | |||||
N0 | 842 | Reference | Reference | ||
N1 | 42 | 6.167 (4.167–9.127) | < 0.001 | 1.525 (0.987–2.357) | 0.057 |
NX | 33 | 5.590 (3.578–8.733) | < 0.001 | 1.710 (1.019–2.869) | 0.042 |
M stage | |||||
M0 | 832 | Reference | Reference | ||
M1 | 72 | 12.173 (8.930–16.590) | < 0.001 | 3.058 (2.125–4.401) | < 0.001 |
MX | 13 | 5.792 (2.950–11.370) | < 0.001 | 2.651 (1.232–5.701) | 0.013 |
CA125 | |||||
Positive | 612 | Reference | Reference | ||
Negative | 302 | 0.219 (0.143–0.334) | < 0.001 | 0.435 (0.272–0.696) | < 0.001 |
Borderline | 3 | 5.078*10^(−7)(0-Inf) | 0.990 | 3.651*10^(−7)(0-Inf) | 0.995 |
Surgery | |||||
No | 5 | Reference | Reference | ||
Yes | 912 | 0.084 (0.034–0.206) | < 0.001 | 0.738 (0.272–2.004) | 0.551 |
Radiation | |||||
Yes | 6 | Reference | Reference | ||
None/Unknown | 911 | 0.156 (0.064–0.380) | < 0.001 | 1.032 (0.394–2.705) | 0.949 |
Chemotherapy | |||||
Yes | 427 | Reference | Reference | ||
No/Unknown | 490 | 0.475 (0.360–0.628) | < 0.001 | 1.565 (1.098–2.231) | 0.013 |