Fig. 2
From: miR-4324 inhibits ovarian cancer progression by targeting FEN1
Downregulation of miR-4324 facilitated tumorigenesis in ovarian cancer. A Cell viability was detected in CaOV3 and OVCAR3 cells transfected with miR-4324 inhibitor and mimic by CCK-8 assay. B Cell proliferation was detected in CaOV3 and OVCAR3 cells transfected with miR-4324 inhibitor and mimic by BrdU assay. C Colony formation number was detected in CaOV3 and OVCAR3 cells transfected with miR-4324 inhibitor and mimic by colony formation assay. D Cell apoptosis level was determined in CaOV3 and OVCAR3 cells transfected with miR-4324 inhibitor and mimic by Caspase 3 kit. E Bax and Bcl-2 protein levels were detected in CaOV3 and OVCAR3 cells transfected with miR-4324 inhibitor and mimic by western blot assay. F Cell adhesion was detected in CaOV3 and OVCAR3 cells transfected with miR-4324 inhibitor and mimic. G Cell migration rate was detected in CaOV3 and OVCAR3 cells transfected with miR-4324 inhibitor and mimic by wound healing assay. *, P < 0.05; **, P < 0.001. NC, negative control; inhibitor, miR-4324 inhibitor; mimic, miR-4324 mimic