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Fig. 3 | Journal of Ovarian Research

Fig. 3

From: Heterozygous FMN2 missense variant found in a family case of premature ovarian insufficiency

Fig. 3

DNA damage models induced by MMC. A Chromosomal breakages in the peripheral lymphocytes obtained from the proband (III-1) and an unrelated control. ↖ denotes the chromosome break point. B Average number of chromosomal breaks in different MMC concentrations. Number of * denotes the degree of difference; ns means nonsense. C Expression of FMN2, P21, and H2AX in different MMC concentrations. performed by Western blot. WT wild type; MT mutant type

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