Detection of plasma exosomal miRNA-205 as a biomarker for early diagnosis and an adjuvant indicator of ovarian cancer staging

Table 3 Relationship between the detected biomarkers and clinicopathological parameters in OC patients

Tested biomarkers	Age (< 50 years vs. ≥ 50 years)	Menopause (Yes vs. No)	Metastases lymph nodes (Yes vs. No)	FIGO stage (stage I + II vs. stage III + IV)	Tumor site (unilateral vs. bilateral
	P value
exosomal miR-205	0.689	0.768	0.007*	0.032*	0.553
exosomal CA125	0.849	0.664	0.292	0.845	0.761
exosomal HE4	0.689	0.520	0.435	0.192	0.665
exosomal TCF21	0.337	0.286	0.588	0.557	0.911
protein CA125(U/mL)	0.614	0.271	0.830	0.614	0.665
protein HE4 (pmol/L)	0.374	0.286	0.934	0.362	0.170

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