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Table 6 Protein target information

From: Investigation of the mechanisms and experimental verification of Cuscuta-Salvia in the treatment of polycystic ovary syndrome (PCOS) via network pharmacology

Gene name

Protein name

Degree

Closeness Centrality

Clustering Coefficient

IL6

Interleukin 6

68

0.87777778

0.51448639

AKT1

RAC-alpha serine/threonine-protein kinase

67

0.86813187

0.52464948

VEGFA

Vascular endothelial growth factor A

64

0.83157895

0.56597222

TP53

Cellular tumor antigen p53

63

0.82291667

0.5483871

MAPK1

Mitogen-activated protein kinase 1

62

0.81443299

0.54680063

TNF

Tumor necrosis factor

62

0.82291667

0.57588577

JUN

Transcription factor AP-1

60

0.7979798

0.58248588

EGF

Pro-epidermal growth factor

59

0.7979798

0.58036236

CASP3

Caspase-3

58

0.78217822

0.61766485

MAPK8

Mitogen-activated protein kinase 8

56

0.76699029

0.63181818