Table 1 Clinicopathological characteristics of patients with OC in this study
From: A risk model of gene signatures for predicting platinum response and survival in ovarian cancer
Variables | Training set(N = 230) | Validation set(N = 75) | ||||
|---|---|---|---|---|---|---|
Resistance (N = 69) | Sensitive (N = 161) | p value | Resistance (N = 34) | Sensitive (N = 41) | p value | |
Age (years, mean ± sd) | 61.77 ± 11.47 | 58.55 ± 11.32 | 0.0524a | – | – | – |
Neoplasm subdivision (Bilateral/Left/Right/−) | 51/7/7/4 | 109/27/14/11 | 0.4066b | – | – | – |
Stage (II / III / IV) | 1/60/8 | 10/127/24 | 0.2167b | – | – | – |
Histologic grade (G2/G3/G4/−) | 7/60/1/1 | 25/133/0/3 | 0.3213b | – | – | – |
Lymphatic invasion (Yes/No/−) | 17/7/45 | 35/30/96 | 0.282b | – | – | – |
Recurrence (Yes/No) | 61/8 | 122/5/34 | 0.06702b | – | – | – |
Death (Dead/Alive/−) | 58/11 | 82/79 | 1.674E-6b | 33/1 | 33/3/5 | 0.6145b |
Overall survival (months, mean ± sd) | 29.71 ± 14.34 | 48.59 ± 25.33 | 1.342E-11a | 27.01 ± 14.51 | 51.82 ± 27.97 | 1.915E-5a |