Table 2 Clinical characteristics of oocyte maturation arrest from the affected patients
From: Mutation analysis of the TUBB8 gene in primary infertile women with oocyte maturation arrest
Case | TUBB8 mutation | Age (years) | Duration of infertility (years) | Previous IVF/ICSI cycles | Total no. of oocytes retrieved | Stage or Stages of Oocytes |
|---|---|---|---|---|---|---|
Family 1, Patient II-1 | c. 938C > T (p. A313V) | 33 | 6 | 1 | 8 | 7 in MI, 1 with abnormal morphologic features |
Family2, Patient II-1 | c.717C > G (p.C239W) | 32 | 5 | 2 | 16 | 15 in MI, 1 with abnormal morphologic features |
Family 3, Patient II-1 | c.752G > A (p.R251Q) | 30 | 3 | 3 | 20 | 20 in MI |
Family 4, Patient II-1 | c.1073C > T(P.P358L) | 27 | 1 | 1 | 14 | 10 in MI, 4 in GV |
Family 5, Patient II-1 | c.286G > A (p.G96R) | 33 | 8 | 2 | 21 | 21 in MI |