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Table 1 Baseline characteristics and clinical outcomes

From: Increasing dominant follicular proportion negatively associated with good clinical outcomes in normal ovarian responders using the depot GnRH agonist protocol: a large-sample retrospective analysis

  Group A < 30% Group B 30%-60% Group C ≥ 60% P
Cycles 398 1230 297 -
Duration of infertility(years) 3.21 ± 1.98 3.35 ± 2.14 2.97 ± 2.06 0.026
Maternal age (years) 29.17 ± 2.94 29.19 ± 2.84 29.13 ± 2.60 0.939
BMI (kg/m2) 22.24 ± 3.03 22.19 ± 3.09 22.42 ± 2.94 0.500
AFC 16.55 ± 6.42 16.39 ± 6.15 14.79 ± 5.01** < 0.001
Basal FSH (mIU/ml) 7.27 ± 1.79 7.23 ± 1.69 7.32 ± 1.94 0.685
AMH (ng/ml) 6.47 ± 4.20 6.59 ± 4.00 5.72 ± 3.52** 0.003
Dose of Gn (IU) 2435.31 ± 962.72 2401.90 ± 855.15 2511.15 ± 811.93 0.149
Duration of Gn (days) 11.31 ± 2.01 11.25 ± 2.11 10.99 ± 1.84 0.087
Dose/Duration of Gn (IU/d) 214.10 ± 70.19 213.27 ± 63.17 228.88 ± 64.52** 0.001
E2 (HCG day, pg/ml) 2322.80 ± 1083.71 2289.81 ± 1047.77 2283.90 ± 1065.46 0.849
P (HCG day, ng/ml) 0.72 ± 0.34 0.79 ± 0.52* 0.82 ± 0.34** 0.010
≥ 14 mm follicles 11.92 ± 3.27 11.21 ± 3.17* 9.45 ± 2.95** < 0.001
Oocytes retrieved 12.74 ± 3.22 12.22 ± 3.35* 11.59 ± 3.29** < 0.001
Oocyte maturation rate (%)     
  IVF 86.10 ± 14.39 88.17 ± 14.22 87.31 ± 14.57 0.101
  ICSI 82.27 ± 14.87 80.59 ± 14.88 81.41 ± 13.05 0.553
Normal fertilisation rate (%)     
  IVF 62.70 ± 16.99 63.26 ± 18.53 61.74 ± 19.25 0.525
  ICSI 57.53 ± 19.46 57.78 ± 19.08 55.16 ± 17.80 0.573
Endometrial thickness (mm) 12.26 ± 2.58 12.30 ± 2.58 12.01 ± 2.38 0.223
Frozen blastocysts 3.05 ± 2.35 2.60 ± 2.16* 2.32 ± 2.12** < 0.001
Blastocyst formation rate (%) 42.38 ± 26.59 38.69 ± 27.16* 38.26 ± 28.27** 0.047
Transfer one embryo     
  Clinical pregnancy rate (%) 58.20 (188/323) 65.30 (510/781) 62.82 (98/156) 0.084
Transfer two embryos     
  Clinical pregnancy rate (%) 68.00 (51/75) 73.94 (332/449) 67.38 (95/141) 0.232
  Implantation rate (%) 48.67 (73/150) 57.57 (517/898) * 50.71 (143/282) 0.031
  1. BMI = body mass index, AFC = antral follicle counting, FSH = follicle stimulating hormone, IVF = in vitro fertilisation, ICSI = intracytoplasmic sperm injection
  2. * Group B versus Group A, P < 0.05; ** Group C versus Group A, P < 0.05