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Table 5 Functions enrichment analysis of GATA family members in ovarian cancer patients

From: Distinct expression and prognostic values of GATA transcription factor family in human ovarian cancer

GO Category Description Count % Log10(P) Log10(q)
GO:0000976 GO Molecular Functions transcription regulatory region sequence-specific DNA binding 31 54.39 −30.16 −25.82
GO:0008134 GO Molecular Functions transcription factor binding 29 50.88 −29.79 −25.75
GO:0017053 GO Cellular Components transcriptional repressor complex 16 28.07 −25.93 −22.49
GO:0007507 GO Biological Processes heart development 24 42.11 −23.46 −20.07
GO:0048568 GO Biological Processes embryonic organ development 22 38.60 −23.18 −19.84
GO:0004089 GO Molecular Functions carbonate dehydratase activity 9 15.79 −19.73 −16.59
hsa00910 KEGG Pathway Nitrogen metabolism 9 15.79 −19.40 −16.71
GO:0051098 GO Biological Processes regulation of binding 18 31.58 −18.58 −15.58
GO:0009611 GO Biological Processes response to wounding 21 36.84 −17.75 −14.83
GO:0035270 GO Biological Processes endocrine system development 12 21.05 −15.67 −12.95
GO:0008593 GO Biological Processes regulation of Notch signaling pathway 11 19.30 −15.18 −12.50
hsa04330 KEGG Pathway Notch signaling pathway 9 15.79 −14.59 −12.20
GO:0042692 GO Biological Processes muscle cell differentiation 15 26.32 −13.90 −11.34
GO:1903706 GO Biological Processes regulation of hemopoiesis 15 26.32 −13.32 −10.81
GO:2000736 GO Biological Processes regulation of stem cell differentiation 9 15.79 −13.14 −10.68
GO:0003300 GO Biological Processes cardiac muscle hypertrophy 10 17.54 −13.13 −10.67
GO:0001816 GO Biological Processes cytokine production 17 29.82 −12.30 −9.95
hsa04658 KEGG Pathway Th1 and Th2 cell differentiation 9 15.79 −11.91 −9.92
GO:0005667 GO Cellular Components transcription factor complex 13 22.81 −11.56 − 9.28
hsa05169 KEGG Pathway Epstein-Barr virus infection 10 17.54 −10.21 −8.29
hsa05161 KEGG Pathway Hepatitis B 9 15.79 −10.14 −8.29
GO:0048645 GO Biological Processes animal organ formation 7 12.28 −9.74 −7.59
GO:0055001 GO Biological Processes muscle cell development 9 15.79 −9.43 −7.31
GO:0032870 GO Biological Processes cellular response to hormone stimulus 14 24.56 −9.04 −6.98
GO:0009408 GO Biological Processes response to heat 8 14.04 −8.72 −6.68
hsa05321 KEGG Pathway Inflammatory bowel disease (IBD) 4 7.02 −4.71 −3.66
hsa04390 KEGG Pathway Hippo signaling pathway 4 7.02 −3.25 −2.40
hsa05031 KEGG Pathway Amphetamine addiction 3 5.26 −3.20 −2.37
hsa05418 KEGG Pathway Fluid shear stress and atherosclerosis 3 5.26 −2.29 −1.57
  1. Notes: The bold values indicate that the results are statistically significant
  2. Abbreviations: GO Gene Ontology, KEGG Kyoto Encyclopedia of Genes and Genomes
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Journal of Ovarian Research

ISSN: 1757-2215

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