Table 1 Clinicopathologic features of patients with ovarian seromucinous borderline tumors with or without endometriosis
From: PAX2, PAX8, and PR are correlated with ovarian seromucinous borderline tumor with endometriosis
Characteristics | All (N = 69) | Without endometriosis (N = 29) | With endometriosis (N = 40) | P value |
|---|---|---|---|---|
Age (yrs) | 35.0 (30.0–43.0) | 33.0 (30.0–44.5) | 35.0 (30.2–41.5) | 0.889 |
BMI (kg/m2) | 20.7 (19.1–22.3) | 20.9 (19.4–23.2) | 20.5 (18.8–22.2) | 0.508 |
Nulliparous | 45 (65.2) | 19 (65.5) | 26 (65.0) | 0.964 |
Menopause | 9 (13.0) | 4 (13.8) | 5 (12.5) | 1.000 |
Borderline op history | 7 (10.1) | 3 (10.3) | 4 (10.0) | 1.000 |
Endometriosis op history | 3 (4.3) | 0 (0) | 3 (7.5) | 0.258 |
ART history | 4 (5.8) | 2 (6.9) | 2(5.0) | 1.000 |
Tumor and treatment | ||||
Serum CA125 (U/ml) | 37.9 (17.6–62.9) | 30.0 (17.1–56.5) | 39.6 (17.3–63.6) | 0.586 |
Normal | 28 (44.4) | 14 (53.8) | 14 (37.8) | 0.208 |
Elevated | 35 (55.6) (n = 63) | 12 (46.2) (n = 26) | 23 (62.2) (n = 37) | |
Tumor size (cm) | 6.3 (4.5–8.3) | 6.0 (4.1–9.5) | 6.3 (4.6–8.2) | 0.894 |
Surgical method | ||||
Laparoscopy | 65 (94.2) | 26 (89.7) | 39 (97.5) | 0.302 |
Laparotomy | 4 (5.8) | 3 (10.3) | 1 (2.5) | |
Tumorectomy method | 0.620 | |||
Cystectomy | 19 (27.5) | 9 (31.0) | 10 (25.0) | |
USO | 38 (55.1) | 14 (48.3) | 24 (60.0) | |
TH with BSO | 12 (17.4) | 6 (20.7) | 6 (15.0) | |
Staging operation | 0.863 | |||
Not done | 23 (33.3) | 10 (34.5) | 13 (32.5) | |
Comprehensive | 46 (66.7) | 19 (65.5) | 27 (67.5) | |
Stage | 0.167 | |||
1A | 29 (42.0) | 11 (37.9) | 18 (45.0) | |
1B | 3 (4.3) | 3 (10.3) | 0 (0) | |
1C | 36 (52.2) | 15 (51.7) | 21 (52.5) | |
2B | 1 (1.4) | 0 (0) | 1 (2.5) | |
Bilaterality of borderline tumor | 5 (7.2) | 3 (10.3) | 2 (5.0) | 0.643 |
Capsule involvement | 5 (7.2) | 4 (13.8) | 1 (2.5) | 0.154 |
Intraepithelial carcinoma | 4 (5.8) | 1 (3.4) | 3 (7.5) | 0.634 |
Microinvasion | 9 (13.0) | 4 (13.8) | 5 (12.5) | 1.000 |
Non- invasive implant | 1 (1.4) | 0 (0) | 1 (2.5) | 1.000 |
Peritoneal cytology | 4 (10.8) (n = 37) | 2 (14.3) (n = 14) | 2 (8.7) (n = 23) | 0.625 |
Pelvic adhesion | 19 (27.5) | 6 (20.7) | 13 (32.5) | 0.278 |
Outcomes | ||||
Pregnancy outcome | 9 (15.8) (n = 57) | 2 (8.7) (n = 23) | 7 (20.6) (n = 34) | 0.288 |
Recurrence of borderline tumor | 3 (4.3) | 0 (0) | 3 (7.5) | 0.258 |
PFS, month | 28.0 (12.5–60.0) | 29.0 (11.5–60.0) | 28.0 (12.5–61.0) | 0.860 |
OS, month | 29.0 (12.5–60.5) | 29.0 (11.5–60.0) | 28.0 (12.5–66.2) | 0.831 |