Peripheral lymphocyte populations in ovarian cancer patients and correlations with clinicopathological features

Table 2 Distribution of peripheral lymphocyte subpopulation in different cohort

	Benign(n = 44)	Borderline(n = 14)	Malignant(n = 112)	P
CD3⁺ T cells (%)	70.06 ± 8.27	69.33 ± 7.76	67.15 ± 9.49	P1 = 0.769^* P2 = 0.075^* P3 = 0.825^*
CD3⁺CD4⁺T cells (%)	38.09 ± 7.00	37.00 ± 12.42	38.59 ± 9.05	P1 = 0.680^* P2 = 0.738^* P3 = 0.552^*
CD3⁺CD8⁺ T cells (%)	30.91 ± 9.90	29.50 ± 7.03	26.84 ± 9.33	P1 = 0.624^* P2 = 0.017^* P3 = 0.307^*
CD8⁺CD28⁺ T cells (%)	9.39 ± 3.00	11.15 ± 7.74	7.31 ± 2.77	P1 = 0.176^* P2 < 0.001^* P3 = 0.054^*
NK cells (CD3⁻CD56⁺) (%)	16.03 ± 7.46	18.72 ± 8.42	18.10 ± 9.06	P1 = 0.259^* P2 = 0.179^* P3 = 0.810^*
Tregs (CD4⁺CD25⁺CD127⁻)(%)	11.82 ± 2.23	13.96 ± 2.89	13.05 ± 3.22	P1 = 0.005^* P2 = 0.021^* P3 = 0.317^*
B cells (CD19⁺) (%)	12.27 ± 5.13	10.56 ± 5.91	12.64 ± 5.28	P1 = 0.299^* P2 = 0.689^* P3 = 0.172^*
CD4/CD8 ratio	1.42 ± 0.71	1.37 ± 0.56	1.78 ± 1.37	P1 = 0.478^# P2 = 0.038^# P3 = 0.274^#

^aNumbers were presented as mean ± standard deviation
^bP values with statistical significance were denoted. P1 = Borderline Vs. Benign;P2 = Malignant Vs. Benign; P3 = Malignant Vs. Borderline
^*Paired T test
^#Mann–Whitney U test

ISSN: 1757-2215