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Table 2 Distribution of peripheral lymphocyte subpopulation in different cohort

From: Peripheral lymphocyte populations in ovarian cancer patients and correlations with clinicopathological features

  Benign(n = 44) Borderline(n = 14) Malignant(n = 112) P
CD3+ T cells (%) 70.06 ± 8.27 69.33 ± 7.76 67.15 ± 9.49 P1 = 0.769* P2 = 0.075* P3 = 0.825*
CD3+CD4+T cells (%) 38.09 ± 7.00 37.00 ± 12.42 38.59 ± 9.05 P1 = 0.680* P2 = 0.738* P3 = 0.552*
CD3+CD8+ T cells (%) 30.91 ± 9.90 29.50 ± 7.03 26.84 ± 9.33 P1 = 0.624* P2 = 0.017* P3 = 0.307*
CD8+CD28+ T cells (%) 9.39 ± 3.00 11.15 ± 7.74 7.31 ± 2.77 P1 = 0.176* P2 < 0.001* P3 = 0.054*
NK cells (CD3CD56+) (%) 16.03 ± 7.46 18.72 ± 8.42 18.10 ± 9.06 P1 = 0.259* P2 = 0.179* P3 = 0.810*
Tregs (CD4+CD25+CD127)(%) 11.82 ± 2.23 13.96 ± 2.89 13.05 ± 3.22 P1 = 0.005* P2 = 0.021* P3 = 0.317*
B cells (CD19+) (%) 12.27 ± 5.13 10.56 ± 5.91 12.64 ± 5.28 P1 = 0.299* P2 = 0.689* P3 = 0.172*
CD4/CD8 ratio 1.42 ± 0.71 1.37 ± 0.56 1.78 ± 1.37 P1 = 0.478# P2 = 0.038# P3 = 0.274#
  1. aNumbers were presented as mean ± standard deviation
  2. bP values with statistical significance were denoted. P1 = Borderline Vs. Benign;P2 = Malignant Vs. Benign; P3 = Malignant Vs. Borderline
  3. *Paired T test
  4. #Mann–Whitney U test