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Table 3 Translational dose of standard drug and SLSO derived from human equivalent dose per day

From: Super-critical fluid extract of Bryonopsis laciniosa (Shivlingi) seeds restores fertility in zebrafish models through revival of cytological and anatomical features

Study groups Standard drug SLSO
Drug Human (mg/day) Translational Dose (µg/kg) Human (mg/day) Translational Dose/day (µg/kg)
0.2X 0.5X 1X 5X 10X 100X
Male Clomiphene 25 0.36 90 0.25 0.64 1.28 6.4 12.8 128
Female Letrozole 2.5 0.036 90 0.25 0.64 1.28 6.4 12.8 128