Table 3 Translational dose of standard drug and SLSO derived from human equivalent dose per day
Study groups | Standard drug | SLSO | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
Drug | Human (mg/day) | Translational Dose (µg/kg) | Human (mg/day) | Translational Dose/day (µg/kg) | ||||||
0.2X | 0.5X | 1X | 5X | 10X | 100X | |||||
Male | Clomiphene | 25 | 0.36 | 90 | 0.25 | 0.64 | 1.28 | 6.4 | 12.8 | 128 |
Female | Letrozole | 2.5 | 0.036 | 90 | 0.25 | 0.64 | 1.28 | 6.4 | 12.8 | 128 |