Fig. 3

Select candidate mutations validated by targeted sequencing: allele fraction and copy number. Panel (A) shows the allelic fraction of mutations and panel (B) shows the tumor copy number for exonic non-synonymous mutations validated by our targeted sequencing panel. Each row represents a specific mutation (with gene name / amino acid change indicated at left) and each column represents a sample. Copy number at each site was 2 in all normal samples (not shown). R = resistant case; S = sensitive case