From: Impact of neoadjuvant chemotherapy on somatic mutation status in high-grade serous ovarian carcinoma
Genes commonly mutated in our study | TCGA-OV number of individuals with mutations (out of a total of 436) |
---|---|
Pre-NACT platinum resistant cases | |
 CSPG4 | 6 |
 SLC35G5 | 0 |
 TUBA3D | 1 |
Pre-NACT platinum sensitive genes | |
 CYP2D6 | 1 |
 NUTM1 | 11 |
 DNAH5 | 42 |
Post-NACT genes exclusively present in the platinum resistant cases | |
 ADGRV1 | 26 |
 MUC17 | 40 |
 MUC20 | 3 |
 PAK2 | 8 |