Fig. 3
From: Wip1 suppresses angiogenesis through the STAT3-VEGF signalling pathway in serous ovarian cancer
A Secretome profiling of differentially expressed cytokines from the culture media of SKOV3/Vector and SKOV3/Wip1 cells. B Overexpression of Wip1 decreased VEGF in SKOV3, HeLa and MDA-MB-231 cells, while knockdown of Wip1 increased VEGF in A2780 and HEY A8 cells. C Representative images of the tube formation of HUVECs/Vector and HUVECs/Wip1. D Statistical analysis of tube branch points. E Immunohistochemical staining of Wip1 and CD31 in peritoneally disseminated nodules in nude mice injected with SKOV3/Vector and SKOV3/Wip1 cells. F Statistical analysis of microvessel density