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Fig. 4 | Journal of Ovarian Research

Fig. 4

From: Wip1 suppresses angiogenesis through the STAT3-VEGF signalling pathway in serous ovarian cancer

Fig. 4

A Relative expression of PPM1D and VEGF mRNA in SKOV3/Vector and SKOV3/Wip1 cells. B Overexpression of Wip1 decreased the expression of VEGF and p-STAT3 (S727) but had no effect on the expression of HIF-1α, STAT3 and p-STAT3 (Y705). C Knockdown of Wip1 increased the expression of VEGF and p-STAT3 (S727) in A2780 cells. D The STAT3 inhibitor Stattic (20 μM) weakened the effect of VEGF upregulation in A2780/shWip1 cells

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