Table 2 Correlation of MAEL expression with patients’ clinico-pathological characteristics in 143 ovarian carcinomas
MAEL protein | ||||
|---|---|---|---|---|
All cases | Normal expression | Overexpression | P value a | |
Age at surgery (years) | 0.547 | |||
≤ 51.5 b | 73 | 36 (49%) | 37 (51%) | |
> 51.5 | 70 | 31 (44%) | 39 (56%) | |
Histological type | 0.696 | |||
Serous | 97 | 45 (46%) | 52 (54%) | |
Mucinous | 16 | 9 (56%) | 7 (44%) | |
Othersc | 30 | 13 (43%) | 17 (57%) | |
Histological grade (Silveberg) | < 0.001 | |||
G1 | 22 | 15 (68%) | 7 (32%) | |
G2 | 83 | 44 (53%) | 39 (47%) | |
G3 | 38 | 8 (21%) | 30 (79%) | |
pT status | 0.032 | |||
pT1 | 41 | 25 (61%) | 16 (39%) | |
pT2 | 26 | 14 (54%) | 12 (46%) | |
pT3 | 76 | 28 (37%) | 48 (63%) | |
pN status | < 0.001 | |||
pN0 | 70 | 45 (64%) | 25 (36%) | |
pN1 | 73 | 22 (30%) | 51 (70%) | |
pM status | 0.045 | |||
pMX | 121 | 61 (50%) | 60 (50%) | |
pM1 | 22 | 6 (27%) | 16 (73%) | |
FIGO stage | 0.004 | |||
I | 25 | 18 (72%) | 7 (28%) | |
II | 15 | 10 (67%) | 5 (33%) | |
III | 81 | 33 (41%) | 48 (59%) | |
IV | 22 | 6 (27%) | 16 (73%) | |