Fig. 4

Kcnq1ot1 competitively binds to miR-506-3p. A The website predicted the targeting relationship between Kcnq1ot1 and miR-506-3p; B-C Dual luciferase reporter gene assay and RNA pull down assay were conducted to verify the targeting relationship between Kcnq1ot1 and miR-506-3p; D RT-qPCR for determining miR-506-3p expression in cells downregulating YY1 or Kcnq1ot1; E Pearson test was carried out to analyze the correlation between miR-506-3p and YY1 in OSCC tissues, n = 98; F Pearson test was implemented to analyze the correlation between miR-506-3p and Kcnq1ot1 in OSCC tissues. * P < 0.05 compared with the Vector group; # P < 0.05 compared with the si-NC group; Measurement data were expressed as mean ± standard deviation