Fig. 1From: Hexokinase 2 promoted cell motility and proliferation by activating Akt1/p-Akt1 in human ovarian cancer cellsHK2 enhances the migration and invasion ability in human ovarian cancer cells in vitro. Stably transfected cell lines were identified by western blotting: (A) SKOV3-GFP and SKOV3-HK2; (D) A2780-shCtr and A2780-shHK2. The migratory capacities were analyzed by the transwell assay, and the number of migratory cells is shown (scale bar, 100 μm): (B) SKOV3-GFP and SKOV3-HK2; (E) A2780-shCtr and A2780-shHK2. The invasive capacities were analyzed by the transwell assay, and the number of migratory cells is shown (scale bar, 100 μm): (C) SKOV3-GFP and SKOV3-HK2; (F) A2780-shCtr and A2780-shHK2. The migratory potential was analyzed by wound-healing assays performed for 0 and 48 h: (G) SKOV3-GFP and SKOV3-HK2; (H) A2780-shCtr and A2780-shHK2. The data are shown as the mean ± SD of three independent experiments. * p < 0.05, ** p < 0.01 vs. control using one-way ANOVABack to article page