Table 2 Cycle characteristics of POSEIDON Group 4 patients with AOA or non-AOA
Parameters | AOA (n = 91) | Non-AOA (n = 168) | P value |
|---|---|---|---|
Stimulation duration (days) | 11.1 ± 2.2 | 11.0 ± 2.1 | 0.684 |
Gonadotropin dosage (IU) | 3132.4 ± 701.0 | 3132.4 ± 697.9 | 1.000 |
Stimulation protocols (%) | 0.807 | ||
GnRH antagonist protocol | 60.4%(55/91) | 64.3%(108/168) | |
PPOS protocol | 27.5%(25/91) | 25.6%(43/168) | |
Ultralong protocol | 12.1%(11/91) | 10.1%(17/168) | |
No. of oocytes retrieved (n) | 4.1 ± 2.6 | 4.5 ± 3.0 | 0.329 |
No. of metaphase II oocytes (n) | 3.2 ± 2.1 | 3.6 ± 2.5 | 0.132 |
Maturation rate (%) | 80.7 ± 20.8 | 82.1 ± 19.3 | 0.581 |
No. of fertilized oocytes (n) | 2.7 ± 1.8 | 3.0 ± 2.1 | 0.258 |
Fertilization rate (%) | 86.2 ± 24.1 | 83.0 ± 26.0 | 0.340 |
Total fertilization failure rate (%) | 3.3% | 4.2% | 0.715 |
No. of Day 3 embryos (n) | 2.6 ± 1.6 | 2.8 ± 2.1 | 0.443 |
Cleavage rate (%) | 94.9 ± 28.0 | 86.5 ± 22.8 | 0.018 |
No. of top-quality Day 3 embryos (n) | 1.4 ± 1.3 | 1.2 ± 1.5 | 0.414 |
≧1 top-quality Day 3 embryos | 73.9% | 55.6% | 0.005 |
Top-quality Day 3 embryos rate (%) | 53.2 ± 39.1 | 37.2 ± 42.7 | 0.004 |
Top-quality Day 3 embryos rate≧50 | 60.2% | 42.5% | 0.008 |