Table 1 Baseline characteristics and ovarian stimulation parameters in the endometrioma and control groups
Variable | Before matching | After matching | ||||
|---|---|---|---|---|---|---|
|  | Endometrioma (OMA) (n = 154) | Control (n = 1913) | P value | Endometrioma (OMA) (n = 154) | Control (n = 305) | P value |
Baseline characteristics | ||||||
Age (years) | 33.55 ± 3.82 | 33.68 ± 4.93 | 0.694 | 33.55 ± 3.82 | 33.65 ± 5.03 | 0.812 |
BMI (kg/m2) | 21.66 ± 2.85 | 22.61 ± 4.19 | 0.000 | 21.66 ± 2.85 | 21.96 ± 2.93 | 0.293 |
Duration of infertility (years) | 2.86 ± 2.09 | 3.33 ± 2.70 | 0.010 | 2.86 ± 2.09 | 2.70 ± 1.90 | 0.396 |
Type of infertility | ||||||
Primary n (%) | 91 (59.09) | 1162 (60.74) | 0.852 | 91 (59.09) | 187 (61.31) | 0.646 |
Secondary n (%) | 63 (40.91) | 751 (39.26) | 63 (40.91) | 118 (38.69) | ||
AMH (ng/mL) | 2.47 ± 2.34 | 3.32 ± 2.96 | 0.000 | 2.47 ± 2.34 | 3.32 ± 2.82 | 0.001 |
AFC (n) | 8.08 ± 5.22 | 12.26 ± 7.41 | 0.000 | 8.08 ± 5.22 | 12.29 ± 7.66 | 0.000 |
Basal FSH (IU/L) | 10.03 ± 6.72 | 8.90 ± 5.00 | 0.044 | 10.03 ± 6.73 | 8.88 ± 4.76 | 0.063 |
Basal LH (IU/L) | 4.85 ± 2.42 | 5.08 ± 4.44 | 0.519 | 4.85 ± 2.42 | 5.25 ± 4.51 | 0.305 |
Basal E2 (pg/ml) | 98.01 ± 270.39 | 124.91 ± 509.70 | 0.518 | 98.01 ± 270.39 | 132.75 ± 494.13 | 0.422 |
Ovarian stimulation parameters | ||||||
Stimulation Protocol | ||||||
Agonist n (%) | 64 (41.56) | 652 (34.08) | 0.030 | 64 (41.56) | 90 (29.51) | 0.010 |
Antagonist n (%) | 70 (45.45) | 1076 (56.25) | 70 (45.45) | 184 (60.33) | ||
Natural or mild stimulation n (%) | 20 (12.99) | 185 (9.67) | 20 (12.99) | 31 (10.16) | ||
Duration of stimulation (days) | 9.66 ± 2.56 | 10.03 ± 2.41 | 0.070 | 9.66 ± 2.56 | 9.89 ± 2.37 | 0.348 |
Total Gn administered (IU) | 2958.93 ± 1141.20 | 2704.04 ± 1118.38 | 0.007 | 2958.93 ± 1141.20 | 2643.20 ± 1086.46 | 0.004 |
E2 on day of hCG (pg/ml) | 2683.47 ± 2131.08 | 3013.27 ± 1989.37 | 0.051 | 2683.47 ± 2131.08 | 3090.01 ± 1948.96 | 0.046 |
Progesterone on day of hCG (ng/ml) | 1.10 ± 0.50 | 1.37 ± 9.08 | 0.712 | 1.10 ± 0.50 | 1.19 ± 0.75 | 0.115 |
Endometrial thickness on day of hCG (mm) | 10.85 ± 2.51 | 10.55 ± 2.50 | 0.147 | 10.85 ± 2.51 | 10.45 ± 2.46 | 0.100 |
Number of follicles ≥ 10 mm on day of hCG | 11.06 ± 7.92 | 13.62 ± 10.13 | 0.002 | 11.06 ± 7.92 | 13.64 ± 9.17 | 0.002 |
Cycle cancellation rate % (n) | 1.30 (2/154) | 1.46 (28/1913) | 1.000 | 1.30 (2/154) | 0.66 (2/305) | 0.605 |