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Table 4 IVF cycle characteristics and outcomes in endometriosis patients with and without prior surgery

From: The presence of ovarian endometrioma adversely affect ovarian reserve and response to stimulation but not oocyte quality or IVF/ICSI outcomes: a retrospective cohort study

Variable

Endometrioma without surgery (n = 104)

Endometrioma with surgery (n = 50)

P value

Age (years)

33.92 ± 4.08

32.88 ± 3.18

0.114

BMI (kg/m2)

21.48 ± 2.86

22.00 ± 2.83

0.293

Duration of infertility (years)

2.85 ± 2.04

2.97 ± 2.22

0.754

AMH (ng/mL)

2.93 ± 2.68

1.61 ± 1.13

0.000

AFC (n)

8.68 ± 5.41

6.92 ± 4.54

0.048

Basal FSH (IU/L)

10.25 ± 7.5448

9.85 ± 5.65

0.747

Duration of stimulation (days)

9.66 ± 2.68

9.72 ± 2.37

0.899

Total Gn administered (IU)

2865.99 ± 1111.65

3198.75 ± 1227.20

0.095

E2 on day of hCG (pg/ml)

3071.55 ± 2425.97

2167.69 ± 1537.13

0.016

Number of follicles ≥ 10 mm on day of hCG

11.73 ± 8.95

7.76 ± 6.33

0.002

Number of oocytes retrieved (n)

9.28 ± 6.74

6.20 ± 4.19

0.001

OSI

3.80 ± 3.48

2.06 ± 1.40

0.000

Number of MII oocytes (n)

7.75 ± 5.90

5.44 ± 3.86

0.004

Oocyte maturity rate % (n)

83.53 (791/947)

87.74 (272/310)

0.075

Number of fertilized oocytes (n)

6.92 ± 5.49

4.74 ± 3.59

0.004

Fertilization rate (%)

81.68 (682/835)

78.45 (233/297)

0.225

Number of Embryos (n)

7.02 ± 5.61

4.96 ± 3.50

0.006

Number of transplantable embryos (n)

6.35 ± 5.35

4.57 ± 3.33

0.013

Number of top-quality embryos (n)

2.53 ± 2.59

1.98 ± 2.22

0.200

Implantation rate % (n)

35.33 (59/167)

43.84 (32/73)

0.211

Cumulative CPRs % (n)

58.24 (53/91)

59.52 (25/42)

0.889

Cumulative LBRs % (n)

57.14 (52/91)

50.00 (21/42)

0.442

  1. BMI, body mass index; AMH, anti-Müllerian hormone; AFC, Antral Follicular Count; E2, estradiol; FSH, follicle-stimulating hormone; Gn, gonadotropin; hCG, human chorionic gonadotropin; OSI, Ovarian sensitivity index; FET, Frozen-thawed ET; MII, Metaphase II, CPRs, Clinical pregnancy rates; LBRs, Live birth rates. Values are expressed as n (%), percentage (%) or mean ± standard deviation (SD) unless otherwise stated. P < 0.05 depicts statistical significance. * depicts P < 0.05 when compared with group (Endometrioma without surgery). ** depicts P < 0.01 when compared with group (Endometrioma without surgery). *** depicts P < 0.001 when compared with group (Endometrioma without surgery). **** depicts P < 0.0001 when compared with group (Endometrioma without surgery).