Fig. 2

Curative and protective effects of XAR™ treatment on adult ovaries and testis. The weight of (A) adult ovaries and (B) testis decreased in both curative and preventive control groups treated with Bu-Cy treatment in female mice and Bu treatment in male mice. On treatment with XAR™ formulation, both the adult ovaries and testis regained significant weight in Bu-Cy and Bu treated mice, suggesting the curative and preventive effect of XAR™. Compared to control, the mice treated only with XAR™ formulation, showed no difference in weight. Two-way ANOVA was used for statistical analysis, ****p < 0.0001, ***p < 0.001, **p < 0.01, *p < 0.05