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Table 3 Multivariable analysis of the association of the variables with CLBR

From: Retrospective analysis of GnRH-a prolonged protocol for in vitro fertilization in 18,272 cycles in China

Independent covariates

Covariate strata

Crude OR (95% CI)

P-value

Adjusted OR (95% CI)

P-value

Age

 

0.90 (0.89–0.90)

< 0.0001

0.93 (0.92–0.94)

< 0.0001

BMI

 

0.98 (0.97–0.99)

< 0.0001

0.98 (0.97–1.00)

0.0062

No. retrieved oocytes

 

Group 1 to Group2

2.66 (2.48–2.86)

< 0.0001

2.07 (1.89–2.26)

0.0003

 

Group1 to Group 3

5.18 (4.66–5.76)

< 0.0001

3.15 (2.75–3.62)

< 0.0001

AFC

 

1.08 (1.07–1.08)

< 0.0001

1.03 (1.02–1.03)

< 0.0001

No. previous treatment cycles/patient

 

0.72 (0.69–0.76)

< 0.0001

0.79 (0.73–0.86)

< 0.0001

Duration of infertility

 

0.94 (0.93–0.95)

< 0.0001

0.98 (0.97–0.99)

0.0002

Cause of infertility

 

Unexplained

1

 

1

 
 

Tubal

1.01(0.94–1.08)

0.8696

0.92 (0.84–1.01)

0.0856

 

Endometriosis

1.20 (1.06–1.35)

0.0032

1.26 (1.08–1.47)

0.0036

 

Anovulatory

0.66 (0.60–0.73)

< 0.0001

1.13 (0.99–1.28)

0.0706

 

Male factor

0.92 (0.86–0.98)

0.0158

1.03 (0.94–1.12)

0.5714

  1. P-values correspond to differences determined by Cox regression analyses with CLBR as the outcome (dependent) variable
  2. AFC Antral follicle count, BMI Body mass index, CI Confidence interval, CLRB Cumulative live birth rate, FSH Follicle-stimulating hormone