Fig. 2

Circ_0000144 upregulation promoted ovarian cancer progression in vitro and in vivo. In SKOV3 and ES-2 cells transfected with pcDNA3.1-circ_0000144 or pcDNA3.1-NC, the expression of circ_0000144 (A) and SLAMF6 (B) was detected by qRT-PCR. C Schematic illustration of circ_0000144 from PCR products, and validation by Sanger sequencing. D Cell proliferation was detected by EDU assay. E and F Cell migration and invasion were monitored. G Tumor volume were measured in response to circ_0000144 overexpression. *P < 0.05