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Fig. 5 | Journal of Ovarian Research

Fig. 5

From: Circular RNA hsa_circ_0000144 aggravates ovarian Cancer progression by regulating ELK3 via sponging miR-610

Fig. 5

MiR-610 negatively regulated ELK3 in ovarian cancer cells. A The predicted binding sites between miR-610 and ELK3 5′UTR by TargetScan. B The luciferase reporter assays were performed to detect the correlation between. C The results showed that miR-610 overexpression group was significantly different from miR-610 inhibitor. MiR-610 negatively regulates ELK3 expression in SKOV3 and ES-2 cells. D In SKOV3 and ES-2 cells transfected with si-ELK3 or si-NC, (D) cell proliferation was detected by EDU assay and (E) colony formation assay. F and G Cell migration and invasion were monitored. *P < 0.05

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